MAG-O3: Transforming Gut Health & Microbiome Diversity

Explore how MAG-O3™ monoglyceride omega-3 enhances gut microbiome health with superior bioavailability, offering a revolutionary approach to gut wellness.
October 27, 2022 by
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MAG-O3 – The Secret to Better Gut Health

Consumers often feel overwhelmed when trying to select the best health supplement to match their unique needs and goals. This is especially true when it comes to Omega-3 Fatty Acids, which are offered in a dizzying array of forms, concentrations, and delivery formats. MAG-O3 simplifies things by offering a revolutionary and scientifically proven omega-3 fish oil in novel monoglyceride form, featuring optimized bioavailability and absorption. Read on to discover why MAG-O3 is your best prebiotic solution to improve gut health and help promote optimal health and wellness now and well into old age.


Omega-3 Fatty Acids & Gut Health

Science has long established that Omega-3 fatty acids play a pivotal role in maintaining mental and physical health. They offer a range of benefits, such as optimizing lipid profile, reducing total cholesterol, lowering high blood pressure, bolstering immune function, improving overall cardiovascular health, sharpening brain function and protecting against age-related cognitive decline and dementia.

 More recent research has shown a direct correlation between a diverse microbiome composition and a high intake of omega-3 fatty acids (EPA and DHA). Indeed, a study published in the International Journal of Molecular Sciences in 2017 revealed that individuals who consume a diet rich in omega-3s had far better bacterial diversity in their gut. This condition correlates with better physical and mental health across the lifespan.


Understanding the Gut Environment

The microbiome refers to the collective microorganisms that live in our gut, while the term microbiota refers to the community of microorganisms themselves. Our gastrointestinal tract houses roughly 100 trillion of these microorganisms, most notably bacteria and various viruses, fungi, and protozoa. These microbes are essential to many critical aspects of health, including immunity, cognition, metabolic health, and endocrine function, among many others.

 Although our gut microbiota is partly inherited, various environmental factors such as physiology, diet, medication use, and lifestyle influence its composition. Of our everyday habits, diet is the one factor that most significantly impacts the composition of our gut microbial community. Fortunately, the gut microbiome is transient, so its composition is continually changing. As such, friendly bacteria (probiotics) can be replenished regularly to maintain a healthy and diverse community of microorganisms and to promote optimal gut health.

Omega-3 Fatty Acids Effectively Modulate the Gut Microbial Community

It would be difficult to discuss the gut microbiome without briefly touching upon probiotics and prebiotics. Indeed, probiotics are live microorganisms (in most cases bacteria) that line the entirety of our digestive tract. These bacteria support the body’s ability to absorb nutrients, promote robust immune function, modulate inflammation, support healthy digestion, and help maintain youthful-looking hair, skin, and nails. On the other hand, prebiotics are nutrients – more precisely, non-digestible carbohydrates (fibres), that serve as food for the healthy microorganisms (probiotics) in our gut. Prebiotics include foods such as chicory root, dandelion greens, and Jerusalem artichoke, among many others. Once consumed, these prebiotic foods not only promote the growth and activity of our friendly bacteria, but their degradation (via fermentation) by probiotics produces Short-Chain Fatty Acids (SCFAs), which are compounds that offer powerful whole-body health benefits. (More on SCFAs later). Omega-3 fatty acids, like the ones contained in MAG-O3, are increasingly being recognized as potent prebiotics that promote a healthy gut microbiome and bolster overall health and wellness.


Omega-3 fatty acids are unique in their ability to improve microbiome diversity, and they do so in a couple of ways:

 A. By modulating the type and abundance of gut microbes & altering the levels of proinflammatory mediators

An adequate intake of omega-3 fatty acids seems to modulate the diversity and abundance of the gut microbiota. Research suggests that omega-3 fish oils exert an inhibitory effect on various bacteria. At the same time, these fatty acids seem to exert beneficial effects on the gut microbiota by:


B. By regulating the levels of short-chain fatty acids

A diet rich in omega-3 fatty acids has been shown to increase the production of anti-inflammatory compounds – most notably, short-chain fatty acids (SCFAs). Healthy gut bacteria produce these SCFAs from the colon's intestinal fermentation of indigestible foods (prebiotics). Acetate, propionate, and butyrate are the three most common SCFAs, and they support the health and healing of cells in the small and large intestines. They are also tasked with maintaining cell homeostasis (balance within the cell) and are the preferred fuel source for the cells lining the colon's interior. These SCFAs have been scientifically shown to improve gut health by maintaining the integrity of the intestinal barrier, regulating mucus production, and modulating the inflammatory response. They can even reduce our risk of cancer (notably, colorectal cancer).


Impact of Improved Microbiome Diversity on Health

A substantial body of evidence has demonstrated that a highly diverse microbiome plays a pivotal role in regulating metabolic, endocrine, and immune functions. Research has been able to identify a range of health benefits, including:


  • Inflammation Modulation and the Prevention of Chronic Inflammation
  • Enhanced Immune Function
  • Better Mood Balance
  • Cognitive Function Support  
  • Cardiovascular Health Promotion & Protection
  • Metabolic Health Support including the prevention and treatment of a cluster of conditions associated with metabolic syndrome such as central obesity, altered glycemic control, insulin resistance, hypertension, non-alcoholic fatty liver disease (NAFLD) and cardiovascular disease (CVD).
  • Prostate Health research on MAG-O3 fish oil has shown that a reduced gut microbiome diversity correlates with prostate cancer. While improving gut microbial diversity may be a novel approach to immunity-based cancer treatments, it is also one that seems extremely promising and one for which MAG-O3 may be exceptionally well suited.


MAG-O3 – Your Best Prebiotic Solution for Optimal Gut Health & Disease Prevention

MAG-O3 is a 100% Canadian innovation that comes to us courtesy of renowned organic chemist Dr. Samuel Fortin and features fish oil in novel monoglyceride form that is presented in a patented delivery format. This state-of-the-art fish oil revolutionizes omega-3 supplements, which have historically demonstrated minimal bioavailability and absorption. Indeed, because MAG-O3 is offered in self-emulsified and pre-digested form, it bypasses the digestive tract altogether, resulting in enhanced absorption in the gastrointestinal tract, where it can be broken down into active metabolites. MAG-O3 supplementation results in up to three times higher plasma concentrations of fatty acids than other forms of omega-3s. It also vastly improves our Omega-3 Index, which is a reliable indicator of our overall health, and predictor of disease risk and potential for longevity.

 It’s also worth noting that for omega-3 fatty acids to impart benefits to specific tissues, they have to be readily absorbed into these target tissues. This feat is problematic with most conventional omega-3 fatty acids like triglycerides (TG) and ethyl esters (EE), both of which have minimal bioavailability and absorption. Here too, MAG-O3 shines thanks to its revolutionary patented delivery system that facilitates the absorption of MAG-EPA and MAG-DHA directly and into target tissues and cells.

 If you’re serious about preserving and protecting your health, MAG-O3 is the obvious choice. Discover MAG-O3 for a healthier, happier, and more diverse gut microbiome.

Buy our MAG-O3™ Products

October 27, 2022
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